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Lindenmayer JP, Khan A, Eerdekens M, Van Hove I, Kushner S (2007) Long-term safety and tolerability of long-acting injectable risperidone in patients with schizophrenia or schizoaffective disorder.

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For other psychotic or delusional disorders, including DI, however, there is a distinct lack of a generally accepted pathogenetic model (further details are given in Inset 13).

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Overdiagnosing” (too many diagnostic investigations just to keep the patient) is not advisable in the long run, but neither is “underdiagnosing” (too early diagnosis of DI without proper tests).

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Interactions of the MAOIs are summarized in Table 14.

This is because of blockade of dopamine receptors in the striatum.

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The detection of laboratory parameters is based on physicochemical reactions between the substance being measured and designed for this purpose.

Concomitant use of Paroxetine with other drugs metabolized by cytochrome CYP2D6 has not been formally studied but may require lower doses than usually prescribed for either Paroxetine or the other drug.

These studies ignore the importance of duration of AP use.

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Another dopamine antagonist is Risperidone (Risperdal) which reduces stuttering by about 50%.

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It is important to emphasize that although the events reported occurred during treatment with Paroxetine, they were not necessarily caused by it.

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However, the observations that the dopamine concentration in the neurointermediate lobe is lower and the basal level of plasma α-MSH is higher in lactating than in cycling female rats () indicate some supporting role for PHDA neurons in the regulation of prolactin secretion during lactation.

For primary DI, a systematic review from our group did not retrieve any published or unpublished controlled trials ().

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